abstract：BACKGROUND:Aggressive behaviour is increased among those with schizophrenia but less is known about those with affective psychoses. Similarly, little is known about aggressive behaviour occurring at the onset of illness. METHOD:The main reasons for presentation to services were examined among those recruited to a UK-b...

journal_title：Psychological medicine

authors： Dean K,Walsh E,Morgan C,Demjaha A,Dazzan P,Morgan K,Lloyd T,Fearon P,Jones PB,Murray RM

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Urban birth, a risk factor for schizophrenia, is more frequent among second-generation immigrants. The aim of the current study was to determine whether the increased risk for schizophrenia found in second-generation immigrants is explained by the degree of urbanization of birthplace and/or factors related t...

journal_title：Psychological medicine

authors： Cantor-Graae E,Pedersen CB

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Suicide is expressly condemned in the Qu'ran, and traditionally few Islamic countries have reported suicide. Undetermined deaths are classified by the World Health Organization (WHO) as Other Violent Deaths (OVD) in ICD-9, or Other External Causes (OEC) in ICD-10. It has been suggested that to avoid under-re...

journal_title：Psychological medicine

authors： Pritchard C,Amanullah S

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:We studied to what extent internet-based cognitive behaviour therapy (CBT) programs for symptoms of depression and anxiety are effective. METHOD:A meta-analysis of 12 randomized controlled trials. RESULTS:The effects of internet-based CBT were compared to control conditions in 13 contrast groups with a tot...

journal_title：Psychological medicine

authors： Spek V,Cuijpers P,Nyklícek I,Riper H,Keyzer J,Pop V

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Developmental adversities may be risk factors for adult suicidal behavior, but this relationship has rarely been studied prospectively. The present study examined the association between childhood adversities and new onset suicidal ideation and attempts in an adult population-based sample. METHOD:The study ...

journal_title：Psychological medicine

authors： Enns MW,Cox BJ,Afifi TO,De Graaf R,Ten Have M,Sareen J

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Pharmaceutical industry funding of psychiatric research has increased significantly in recent decades, raising the question of a relationship between pharmaceutical company funding of clinical psychiatric studies and the outcomes of those studies. This study examines this relationship. METHOD:Abstracts of a...

journal_title：Psychological medicine

authors： Kelly RE Jr,Cohen LJ,Semple RJ,Bialer P,Lau A,Bodenheimer A,Neustadter E,Barenboim A,Galynker II

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups ar...

journal_title：Psychological medicine

authors： Fearon P,Kirkbride JB,Morgan C,Dazzan P,Morgan K,Lloyd T,Hutchinson G,Tarrant J,Fung WL,Holloway J,Mallett R,Harrison G,Leff J,Jones PB,Murray RM,AESOP Study Group.

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:There is evidence that cannabis use might be relevant to the aetiology of schizophrenia. We aimed to measure any change in cannabis use over time in those first presenting with schizophrenia in South-East London from 1965 to 1999, and compare this with change in use in those presenting with non-psychotic psy...

journal_title：Psychological medicine

authors： Boydell J,van Os J,Caspi A,Kennedy N,Giouroukou E,Fearon P,Farrell M,Murray RM

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The diagnosis of bipolar disorder in pre-pubertal populations remains difficult and often controversial. Consequently, the clinical and neuropsychological characteristics of mania in the child and adolescent years remain poorly defined. This review provides a clinical account of childhood and adolescent bipo...

journal_title：Psychological medicine

authors： Kyte ZA,Carlson GA,Goodyer IM

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Bright light and high-density negative air ion exposure are efficacious for winter and non-seasonal depression compared with a low-density negative ion placebo. Similarly, auditory stimuli improve mood in clinical populations. This study compared the short-term effects of bright light, an auditory stimulus, ...

journal_title：Psychological medicine

authors： Goel N,Etwaroo GR

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Abnormal perceptions of food and shape underpin the cognitive behavioural model of eating disorders (EDs). The aim of this study was to investigate motivational processing of disorder-specific and standard emotional cues in anorexia (AN) and bulimia nervosa (BN) using startle eyeblink modulation (SEM). SEM w...

journal_title：Psychological medicine

authors： Friederich HC,Kumari V,Uher R,Riga M,Schmidt U,Campbell IC,Herzog W,Treasure J

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Patients may present with cognitive impairment in the euthymic phase of affective disorder, but it is unclear whether the impairment is prevalent before onset of the illness. The aim of the present study was to examine the hypothesis that genetic liability to affective disorder is associated with cognitive i...

journal_title：Psychological medicine

authors： Christensen MV,Kyvik KO,Kessing LV

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Emotional Stroop tasks have shown attention biases of clinical populations towards stimuli related to their condition. Asperger Syndrome (AS) is a neuropsychiatric condition with social and communication deficits, repetitive behaviours and narrow interests. Social deficits are particularly striking, includin...

journal_title：Psychological medicine

authors： Ashwin C,Wheelwright S,Baron-Cohen S

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Gulf War veterans have a number of health complaints. We therefore decided to carry out a systematic review to identify and summarize the findings from studies that have assessed multi-symptom conditions in Gulf War veterans and in an unexposed comparison group. METHOD:Studies published between January 1990...

journal_title：Psychological medicine

authors： Thomas HV,Stimpson NJ,Weightman AL,Dunstan F,Lewis G

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Spousal concordance for common mental disorders provides evidence of the relevance of social contextual factors. There are, however, limitations within the existing literature examining spousal similarity in mental health and little consensus as to the causes of spousal similarity. This study considers a lar...

journal_title：Psychological medicine

authors： Butterworth P,Rodgers B

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Cognitive models propose that auditory verbal hallucinations arise through defective self-monitoring and external attribution of inner speech. We used a paradigm that engages verbal self-monitoring to examine how deficits in this process are related to symptoms and diagnosis in patients with psychosis. METH...

journal_title：Psychological medicine

authors： Johns LC,Gregg L,Allen P,McGuire PK

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Prevalence of childhood anxiety disorders at specific ages and genetic etiological influences on anxiety disorders in young children have been little studied. The present study reports prevalence estimates in a community sample of 6-year-old twins, and patterns of genetic and environmental influences on thes...

journal_title：Psychological medicine

authors： Bolton D,Eley TC,O'Connor TG,Perrin S,Rabe-Hesketh S,Rijsdijk F,Smith P

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:There have been conflicting reports on time trends in urban-rural differences in the incidence of schizophrenia. This study explored the potential time trends in these differences with regard to birth cohort and age at onset. METHOD:Linking data from the Danish Civil Registration system with data from the D...

journal_title：Psychological medicine

authors： Pedersen CB

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:The frequency and clinical, neuropsychological and neuroimaging correlates of apathy in patients who have had a stroke are inadequately defined. METHOD:A total of 167 consecutive patients admitted to the stroke units of two university hospitals after an ischaemic stroke and 109 controls received extensive m...

journal_title：Psychological medicine

authors： Brodaty H,Sachdev PS,Withall A,Altendorf A,Valenzuela MJ,Lorentz L

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Excessive worry is required by DSM-IV, but not ICD-10, for a diagnosis of generalized anxiety disorder (GAD). No large-scale epidemiological study has ever examined the implications of this requirement for estimates of prevalence, severity, or correlates of GAD. METHOD:Data were analyzed from the US Nationa...

journal_title：Psychological medicine

authors： Ruscio AM,Lane M,Roy-Byrne P,Stang PE,Stein DJ,Wittchen HU,Kessler RC

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Overall findings of our first direct interview family study of obsessive-compulsive disorder (OCD) indicated that OCD is familial. In this replication study, we carefully examined the role of informant data in ascertaining OCD in relatives. METHOD:We interviewed 112 relatives of 57 OCD patients and 115 rela...

journal_title：Psychological medicine

authors： Lipsitz JD,Mannuzza S,Chapman TF,Foa EB,Franklin ME,Goodwin RD,Fyer AJ

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:The objective was to describe patients presenting themselves at emergency-care settings following a suicide attempt in eight culturally different sites [Campinas (Brazil), Chennai (India), Colombo (Sri Lanka), Durban (South Africa), Hanoi (Viet Nam), Karaj (Iran), Tallinn (Estonia), and Yuncheng, (China)]. ...

journal_title：Psychological medicine

authors： Fleischmann A,Bertolote JM,De Leo D,Botega N,Phillips M,Sisask M,Vijayakumar L,Malakouti K,Schlebusch L,De Silva D,Nguyen VT,Wasserman D

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Few epidemiological studies have examined the temporal relationship between chronic pain and depression using longitudinal data. In the present study, we examined major depression as both an antecedent risk factor and consequence of chronic back pain (CBP) in the general population. METHOD:Data on 9909 pain...

journal_title：Psychological medicine

authors： Currie SR,Wang J

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:We assess claims that the documented rise in psychiatric morbidity during the nineteenth and twentieth centuries was associated with an increasing incidence of schizophrenia. METHOD:Cross-sectional epidemiological comparison of the incidence of schizophrenia in one urban, industrialized community at three p...

journal_title：Psychological medicine

authors： Nixon NL,Doody GA

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Schizophrenia is associated with perceptual organization deficits and abnormal neuronal connectivity has been described in early visual areas. The purpose of this study was to investigate the functional integrity of lateral connections in early visual areas of patients with schizophrenia and type I bipolar d...

journal_title：Psychological medicine

authors： Kéri S,Kelemen O,Benedek G,Janka Z

更新日期：2005-07-01 00:00:00

abstract：:The Committee on Chronotherapeutics, delegated by the International Society for Affective Disorders (ISAD), makes the following recommendations after reviewing the evidence as of November 2004. (1) Wake therapy is the most rapid antidepressant available today: approximately 60% of patients, independent of diagnostic s...

journal_title：Psychological medicine

authors： Wirz-Justice A,Benedetti F,Berger M,Lam RW,Martiny K,Terman M,Wu JC

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Several lines of evidence indicate a role of the brain-derived neurotrophic factor (BDNF) in the modulation of eating behaviour. Therefore, alterations in the physiology of this neurotrophin may be involved in the pathogenesis of eating disorders. In the present study, we investigated serum levels of BDNF in...

journal_title：Psychological medicine

authors： Monteleone P,Fabrazzo M,Martiadis V,Serritella C,Pannuto M,Maj M

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:In the conditioned fear paradigm, repeated pairing of an aversive unconditioned stimulus (US) (e.g. electric shock) with a neutral conditioned stimulus (CS) (e.g. bright light) results in a conditioned fear response to the light alone. Animal studies have shown that the amygdala plays a critical role in acqu...

journal_title：Psychological medicine

authors： Bremner JD,Vermetten E,Schmahl C,Vaccarino V,Vythilingam M,Afzal N,Grillon C,Charney DS

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Recent neurobiological models provide a possible mechanism of daily life stress directly affecting the intensity of psychotic experiences in vulnerable individuals. In order to validate such a mechanism, the impact of daily life stress on psychosis intensity was investigated in two groups at increased risk o...

journal_title：Psychological medicine

authors： Myin-Germeys I,Delespaul P,van Os J

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Little research has examined genetic and environmental contributions to psychopathic personality traits. Additionally, no studies have examined etiological connections between psychopathic traits and the broad psychopathological domains of internalizing (mood and anxiety) and externalizing (antisocial behavi...

journal_title：Psychological medicine

authors： Blonigen DM,Hicks BM,Krueger RF,Patrick CJ,Iacono WG

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Classification of psychosis lacks a biological basis and current diagnostic categories may obscure underlying continuities. Data reduction methods of symptom profiles within a population-based cohort of people with a wide range of affective and non-affective psychoses may permit an empirical classification o...

journal_title：Psychological medicine

authors： Murray V,McKee I,Miller PM,Young D,Muir WJ,Pelosi AJ,Blackwood DH

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:In resource-poor countries, there remains an alarming treatment gap for people with schizophrenia, particularly those living in rural areas. Decentralization of mental health services, including community-based outreach programmes, represents one obvious strategy for bringing appropriate care to these commun...

journal_title：Psychological medicine

authors： Srinivasa Murthy R,Kishore Kumar KV,Chisholm D,Thomas T,Sekar K,Chandrashekari CR

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:The goal of this study is to determine the association between panic attacks in adolescence and the risk of personality disorders during young adulthood. METHOD:Data were drawn from the Children in the Community Study, a longitudinal epidemiological study of psychopathology across the life-course in 717 indi...

journal_title：Psychological medicine

authors： Goodwin RD,Brook JS,Cohen P

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:Cognitive therapy (CT) for bipolar disorder emphasizes the monitoring and regulation of mood, thoughts and behaviour. The Sense of Hyper-Positive Self Scale (SHPSS) measures the extent to which bipolar patients value themselves and perceive themselves to possess personal attributes (e.g. dynamism, persuasi...

journal_title：Psychological medicine

authors： Lam D,Wright K,Sham P

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Previous research has found that depression is a major cause of memory complaints. However, there is evidence that memory complaints also weakly predict cognitive decline and dementia. The present study examined a range of possible determinants of memory complaints, covering psychiatric and personality facto...

journal_title：Psychological medicine

authors： Jorm AF,Butterworth P,Anstey KJ,Christensen H,Easteal S,Maller J,Mather KA,Turakulov RI,Wen W,Sachdev P

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Controlled prospective studies of the simultaneous long-term outcome of several mental disorders are rare. This study sought to determine if there were important differences between the outcome of anxiety and depressive disorders after 12 years and to examine their main predictors. METHOD:A cohort of 210 pe...

journal_title：Psychological medicine

authors： Tyrer P,Seivewright H,Johnson T

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Based on prevalence studies and the few incidence studies of pervasive developmental disorders (PDDs) the prevalence and incidence of these disorders have been claimed to be increasing. METHOD:The annual and age-specific prevalence and incidence rates of childhood autism, atypical autism, Asperger's disorde...

journal_title：Psychological medicine

authors： Lauritsen MB,Pedersen CB,Mortensen PB

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Results of previous research examining long-term residual effects of marijuana use on cognition are conflicting. A major methodological limitation of prior studies is the inability to determine whether differences between users and non-users are due to differences in genetic vulnerability preceding drug use ...

journal_title：Psychological medicine

authors： Lyons MJ,Bar JL,Panizzon MS,Toomey R,Eisen S,Xian H,Tsuang MT

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Previous work suggests that individuals with schizophrenia display an altered homovanillic acid (HVA) response to metabolic stress. The present study replicated and extended this paradigm, including individuals with elevated genetic risk for schizophrenia. METHOD:Patients with psychosis (n = 50), non-psycho...

journal_title：Psychological medicine

authors： Marcelis M,Cavalier E,Gielen J,Delespaul P,Van Os J

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Chronic fatigue is a common condition, frequently presenting in primary care. The aim of this study was to compare the cost-effectiveness of cognitive behavioural therapy (CBT) and graded exercise therapy (GET), and to compare therapy with usual care plus a self-help booklet (BUC). METHOD:Patients drawn fro...

journal_title：Psychological medicine

authors： McCrone P,Ridsdale L,Darbishire L,Seed P

更新日期：2004-08-01 00:00:00